Because “studies show” isn’t enough.
18 papers, tiered on a transparent rubric. Read the evidence your supplement rests on — before you swallow it.
Explore research pillars
Editor's picks
The Iron Paradox: Why Taking More Iron Can Actually Make You Absorb Less
Melatonin's Sleep Benefits Peak at Higher Doses Than Most People Take
Latest research
Vitamin C's Collagen Synthesis Pathway Links Bone Density to Blood Pressure
Magnesium May Be the Missing Link for Better Sleep Quality
N-Acetylcysteine: The Hospital Staple Quietly Becoming One of the Most Versatile Supplements in Medicine
Niacin: The Forgotten Vitamin That Reshapes Your Cholesterol Profile — But at a Price
L-Citrulline: The Amino Acid Your Body Converts to Arginine Better Than Arginine Itself
Bacopa Monnieri May Sharpen Memory in Aging Adults, But Patience Is Required
Quercetin Lowers Blood Pressure and Cholesterol, But Your Body Barely Absorbs It
Alpha-Lipoic Acid: A Mitochondrial Antioxidant With Real Benefits for Blood Sugar, Nerve Pain, and Inflammation
Zinc Does Far More Than Fight Colds — Here's What the Research Actually Shows
Browse by health goal
Metabolic Health
6 articles · Magnesium · Nac · Niacin
Cardiovascular & Circulation
8 articles · Vitamin C · Magnesium · Niacin
Brain, Mood & Cognitive Performance
3 articles · Bacopa Monnieri · Lions Mane · L Theanine
Sleep & Recovery
4 articles · Magnesium · Melatonin · L Theanine
Hormonal Health
1 article · Zinc
Muscle, Bone & Joint
0 articles
Immune System Health & Inflammation
5 articles · Vitamin C · Nac · Quercetin
Cellular Longevity & Healthy Aging
5 articles · Nac · Alpha Lipoic Acid · Vitamin C
Gut & Microbiome
0 articles
Skin, Hair & Collagen
0 articles
Explore by pillar
Every claim gets the same rubric.
We don’t rate supplements — we rate claims about supplements. A single ingredient can earn Strong evidence for one benefit and Insufficient for another. The tier tells you how seriously to take a specific conclusion, not the molecule in general.
At least two concordant RCTs with low-to-moderate risk of bias, or a high-certainty GRADE meta-analysis. This is where we feel confident saying yes.
One well-designed RCT plus replicated observational data. The signal is real; the effect size isn’t locked down.
Early human data, mixed results, or a single trial. We report it, but we don’t bet the farm on it.
Animal-only studies, mechanism-only claims, or anecdote. We index these so you know they exist, not so you swallow them.












