Aviado Research
Every study, tiered and tagged.
270 peer-reviewed studies, indexed by evidence tier, supplement, and health goal across 10 domains and 84 ingredients. Filter to find the research that actually addresses your question.
Aviado Research
Spirulina's Effect on Liver Enzymes Is Fast and Measurable — But Only If Your Baseline Is Elevated
Why Your Liver Panel Predicts Spirulina's True Impact
Aviado Research
Aviado Research
Sage Extract Cuts LDL by 35% in 3 Months — But Only Some People See the Glucose Drop
New RCTs reveal a lipid-lowering edge, but glucose effects depend on your metabolic profile
Aviado Research
Aviado Research
Aviado Research
How Zinc Ions Block Inflammatory Cascades via NF-κB and Cytokine Control
Zinc’s Molecular Role in Reducing Systemic Inflammation and C-Reactive Protein
Aviado Research
Aviado Research
How Vitamin B6 Converts to PLP to Power 150+ Enzyme Reactions
The Central Role of Pyridoxal 5-Phosphate in Human Metabolism and Health
Aviado Research
Aviado Research
Quercetin's Anti-Inflammatory Path: IL-6 Suppression vs Oxidative Defense
Contrasting Human Evidence for Cytokine Modulation and Antioxidant Enzyme Activation
Aviado Research
How Nicotinamide Riboside Boosts NAD+ to Power Cellular Energy Systems
Mechanisms and Human Evidence Linking NR, NAD+, and Mitochondrial Health
Aviado Research
How Ginsenosides Target IL-6 Inflammation Through Multiple Pathways
Panax ginseng’s anti-inflammatory effects are anchored in TLR4/MyD88/NF-κB signaling and dose-dependent IL-6 reduction
Aviado Research
Aviado Research
Astaxanthin Reduces Lipid Peroxidation via Membrane Protection
A Mechanistic Deep Dive into Astaxanthin's Role in Safeguarding Cell Membranes and Reducing Oxidative Stress
Aviado Research
CoQ10's Dual Role: Electron Transport Plus Ferroptosis Protection
The mitochondrial and ferroptosis-blocking actions that underpin CoQ10’s clinical relevance
Aviado Research
How Niacin's GPR109A Receptor Triggers Dual Lipid and Inflammation Control
Unpacking the Mechanistic Links Between Niacin Supplementation, Fat Metabolism, and Immune Modulation
Aviado Research
How Lactobacillus Strains Lower Liver Enzymes Through Gut Barrier Repair
Mechanisms, human trial evidence, and practical interpretation for liver health biomarkers
Aviado Research
Aviado Research
Cordycepin Activates AMPK to Reduce Inflammation While Boosting HDL
Cordyceps militaris’s signature molecule targets metabolic and inflammatory pathways in human studies
Aviado Research
How Biotin Activates Carboxylase Enzymes to Control Fat and Glucose
Mechanistic Insights and Human Evidence for Biotin’s Role in Metabolic Regulation
Aviado Research
How Folate's One-Carbon Pathway Controls Insulin, Inflammation & Vessels
Biochemical Mechanisms Linking Folate Supplementation to Metabolic and Vascular Outcomes
Aviado Research
How Green Tea's EGCG Blocks DPP-4 and Pancreatic Lipase Enzymes
Dual Enzyme Inhibition as a Plausible Metabolic Mechanism
Aviado Research
L-Carnitine's Dual Pathway: Beta-Oxidation Enhancement vs TMAO Production
Balancing Mitochondrial Benefits and Metabolic Tensions
Aviado Research
Aviado Research
How Astragalus Polysaccharides Reset Inflammatory Balance Through IL-6/IL-10
Consistent Cytokine Modulation Explains Astragalus' Cardiometabolic Benefits
Aviado Research
Inside ProofMark: How Aviado Scores Every Supplement for Quality and Trust
Decoding the ProofMark Score—What It Tells You About The Supplements You Take
Aviado Research
Immune Health After 40: Mastering the Balance Between Defense and Inflammation
A Comprehensive Guide for Men 40–65 to Reclaim Immune Resilience
Aviado Research
Midlife Metabolism: Why Your Body Changed the Rules (And How to Take Back Control)
A comprehensive, evidence-based guide for women 40-55 facing perimenopausal metabolic shifts
Aviado Research
Metabolic Health in Women 18-39: Beyond Calories, Into Hormones
A Comprehensive Guide to Tracking, Optimizing, and Understanding Your Metabolism in Your Reproductive Years
Aviado Research
The Insulin Resistance Spectrum: Why 'Normal' Glucose Can Hide a Decade of Metabolic Risk
Uncovering the Hidden Years Before Blood Sugar Rises
Aviado Research
Menopause and Your Brain: Mastering Cognitive Health After 40
A Comprehensive Guide for Women Navigating Hormonal Transitions
Aviado Research
Peak Mental Performance: The Comprehensive Guide for Men 18–39
How to Protect and Upgrade Your Brain for Life’s Most Demanding Decade
Aviado Research
Hormonal Health in Your 20s and 30s: Why Your Menstrual Cycle Is Your Fifth Vital Sign
A Comprehensive Guide for Women Navigating Hormones, Fertility, and Health Data
Aviado Research
Cellular Longevity for Men 18-39: The Science and Strategy to Age Well—Starting Now
How Early Action on Cellular Health Sets Your Biological Clock for Decades
Aviado Research
Why Your Gut Barrier Breaks Down First - And How to Track It Before Disease Develops
Zonulin as Your Earliest Gut Warning System and What to Do About It
Aviado Research
Why Your Vitamin C Levels Predict Bone Loss Better Than Your Age
How Tracking This Overlooked Nutrient Can Help You Protect Your Bones—At Any Stage of Life
Aviado Research
Aviado Research
Calcium's Hidden Metabolic Job: Why Your HDL, Triglycerides, and Blood Pressure All Respond Differently to the Same Dose
Personalizing Calcium for Metabolic Health Goes Beyond Bones
Aviado Research
Your Iron Status Is Quietly Distorting Your HbA1c — And Most Doctors Aren't Checking
Why personalizing your iron panel is the missing key to accurate metabolic health — and how to use supplement science to get it right
Aviado Research
Aviado Research
Aviado Research
Niacin Raises HDL and Lowers Lp(a) — But Also Worsens Insulin Resistance: How to Know If the Trade-Off Works for You
A Deep Dive into Niacin's Unique Cardiometabolic Effects and How to Personalize Its Use
Aviado Research
Milk Thistle's Hidden Metabolic Upgrade: The Liver Supplement That Also Drops Blood Sugar 22 mg/dL and Rewires Insulin Resistance
Why metabolic markers—not just liver enzymes—reveal milk thistle's real benefits
Aviado Research
Your MTHFR Genotype Determines Whether Folic Acid Helps or Harms You — and Most People Never Check
Personalized Folate Supplementation: Why Your Genes and Blood Markers Matter More Than the Label
Aviado Research
Why Your Magnesium Supplement May Be Working—Just Not Where You're Looking
Magnesium's metabolic and blood pressure benefits are real, but most people are tracking the wrong results.
Aviado Research
Vitamin C Works Differently If You Have Type 2 Diabetes — And the Gap Is Enormous
Why Vitamin C Moves Cardiometabolic Markers Only in People with Metabolic Dysfunction
Aviado Research
Ginseng Works—But Only If You're the Right Kind of Inflamed
Why Panax ginseng’s benefits depend on your metabolic and inflammatory baseline
Aviado Research
Low Plasma Glycine Is a Metabolic Warning Signal — and Most People with Obesity or Insulin Resistance Have It
Why Measuring and Supplementing Glycine May Change the Way We Detect and Improve Metabolic Health
Aviado Research
Quercetin's Results Depend on Whether You're Sick or Healthy — And Most Studies Mix the Two
Why Personal Health Status, Not Just Dosage, Is the Real On/Off Switch for Quercetin Benefits
Aviado Research
Berberine Works — But Only If Your Gut Can Activate It: The Microbiome Key Most Users Are Missing
Why gut health is the missing factor behind berberine's wildly inconsistent results
Aviado Research
Aviado Research
Taurine's Blood Pressure Effect Is Real — But Only If You're a Responder. Here's How to Find Out
Meta-analyses show consistent cardiovascular benefits, but metabolic status determines who sees results
Aviado Research
ALA Cuts Inflammation Markers Reliably — But Its Metabolic Effects Only Show Up in Certain People
Why Alpha-Lipoic Acid Is a Proven Anti-Inflammatory, and How to Tell If You're a Metabolic 'Responder'
Aviado Research
Resveratrol Works — But Only If You Have the Right Metabolic Profile
Why metabolic dysfunction—not dose—predicts who benefits from this popular supplement
Aviado Research
Zinc's Benefits Are Real — But Only If You're Actually Deficient
Meta-analyses reveal zinc supplementation dramatically improves metabolic markers in diabetics while potentially lowering HDL in healthy people
Aviado Research
Your Vitamin K2 Supplement May Be Working—But Not Where You Think It Is
Why measuring osteocalcin carboxylation determines whether you'll see metabolic benefits from K2
Aviado Research
Metabolic Health in Women 18-39: Beyond Calories, Into Hormones
A Comprehensive Guide to Tracking, Optimizing, and Understanding Your Metabolism in Your Reproductive Years
Aviado Research
Metabolic Health for Young Men: Why Your Blood Sugar Matters More Than You Think
A Comprehensive Guide to Optimizing Glucose, Insulin, and Lifelong Health in Your 20s and 30s
Aviado Research
Midlife Metabolism: Why Your Body Changed the Rules (And How to Take Back Control)
A comprehensive, evidence-based guide for women 40-55 facing perimenopausal metabolic shifts
Aviado Research
Metabolic Health After 40: Why Your Engine Needs a Tune-Up
A Deep Dive for Men 40-65: Biomarkers, Interventions, and What Really Works
Aviado Research
Aviado Research
Metabolic Health After 55: The Silent Shift That Changes Everything
How menopause rewires your metabolic machinery and what to do about it
Aviado Research
Metabolic Health After 65: Why Your Muscles Are Your Best Medicine
Breaking the cycle of muscle loss and insulin resistance that accelerates aging in older men
Aviado Research
The Clock vs. The Speedometer: Why Biological Age Measurement Has Two Fundamentally Different Jobs
Understanding the difference between where you are in aging and how fast you're aging
Aviado Research
The Lipid Biomarker Decision Tree: Why Your Standard Cholesterol Panel Misses Half the Story
Understanding the four distinct cardiovascular risk pathways that basic lipid panels can't distinguish
Aviado Research
The Four Blood Signals That Predict Brain Aging — And Why Most Doctors Don't Test Them
How neurotrophins, plasmalogen lipids, inflammatory cytokines, and metabolic markers reveal brain health years before symptoms appear
Aviado Research
The Insulin Resistance Spectrum: Why Two People With the Same Fasting Glucose Have Completely Different Metabolic Risk
Understanding compensated versus decompensated insulin resistance reveals hidden metabolic dysfunction years before diabetes appears
Aviado Research
Aviado Research
Inulin's Gut-to-Blood Pipeline: Why Your Microbiome Decides Whether It Works
Why the Right Gut Bacteria Are the Real Key to Inulin’s Benefits
Aviado Research
NR Reliably Raises Your NAD+ — But Whether That Translates to Any Clinical Benefit Depends Entirely on Who You Are
Nicotinamide riboside's universal NAD+ boost is just the starting line — not everyone gets a clinical win
Aviado Research
Aviado Research
Your Lactobacillus Strain Is the Variable: Why Most Probiotic Research Misses the Point
Network meta-analyses reveal only certain Lactobacillus strain combinations actually move the needle—are you taking the one that works for your biomarker?
Aviado Research
Your Spermidine Supplement May Not Be Reaching Your Blood — And No One Told You
New research reveals the absorption paradox that makes most spermidine supplementation ineffective
Aviado Research
The Bifidobacterium Paradox: Same Probiotic, Opposite Effects on LDL and HbA1c Depending on Which Strain and Who You Are
Network meta-analyses reveal strain-specific effects that can either help or harm your cardiometabolic markers
Aviado Research
Your Selenium Level Is Either Too Low or Too High — and Standard Dosing Can't Tell You Which
New dose-response data reveals 3-fold variation in blood levels between people taking identical selenium doses
Aviado Research
Astragalus Cuts HbA1c by Up to 1.77% — But Only If You're in the Right Half of Responders
What Meta-Analyses Reveal About Astragalus, Blood Sugar, and Why Your Body May Be the Real Variable
Aviado Research
Your HbA1c Number May Be Lying to You — And Genetics Explains Why
Up to 40% of people have systematic differences between their HbA1c and actual glucose exposure
Aviado Research
Your Homocysteine Level Is a Personal Report Card on Your Methylation Genetics — Here's How to Read It
Why two people with identical diets and supplements can have wildly different homocysteine levels
Aviado Research
The metformin interaction that makes berberine more complicated for people already on diabetes medication
New crossover trial reveals dose-dependent pharmacokinetic interaction between goldenseal and metformin in type 2 diabetes patients
Aviado Research
How Insulin Signaling Works: The Two-Fork Pathway That Controls Both Metabolism and Cell Growth
One receptor, two major cascades, and a critical branch point that shapes health and disease
Aviado Research
Aviado Research
Aviado Research
Aviado Research
Best Supplements for LDL Cholesterol: What the Evidence Actually Shows
Aviado Research
Best Supplements for HbA1c (Blood Sugar Control): What the Evidence Actually Shows
Aviado Research
