May 122026
18 min · 14 sources
Aviado Research
Aviado Research
Aviado Research · Browse
Every study, tiered and tagged.
270 peer-reviewed studies, indexed by evidence tier, supplement, and health goal across 10 domains and 84 ingredients. Filter to find the research that actually addresses your question.
Brain, Mood & Cognitive Performance
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270 results
May 112026
Krill Oil Reliably Cuts Triglycerides—But Leaves Cholesterol Untouched: What That Split Tells You About Your Own Response
A Deep Dive into the Biomarker-Specific Effects and Personalizable Value of Krill Oil Supplementation
7 min · 8 sources
Aviado Research
Aviado Research
May 82026
Sage Extract Cuts LDL by 35% in 3 Months — But Only Some People See the Glucose Drop
New RCTs reveal a lipid-lowering edge, but glucose effects depend on your metabolic profile
8 min · 8 sources
Aviado Research
Aviado Research
May 52026
How Zinc Ions Block Inflammatory Cascades via NF-κB and Cytokine Control
Zinc’s Molecular Role in Reducing Systemic Inflammation and C-Reactive Protein
9 min · 9 sources
Aviado Research
Aviado Research
May 52026
9 min · 8 sources
Aviado Research
Aviado Research
May 42026
How Vitamin A's Retinoid Pathway Controls Iron Transport and Hemoglobin
Retinoic acid receptor signaling as a regulator of iron mobilization and blood health
9 min · 8 sources
Aviado Research
Aviado Research
May 42026
How B-Complex Vitamins Lower Homocysteine Through Methylation Pathways
Mechanistic Evidence and Practical Insights for Cardiovascular Biomarker Optimization
9 min · 10 sources
Aviado Research
Aviado Research
May 42026
Sulforaphane Activates Phase II Detox Enzymes Through Nrf2 Signaling
Broccoli sprout-derived sulforaphane enhances glutathione conjugation for measurable detoxification
9 min · 8 sources
Aviado Research
Aviado Research
May 42026
How Vinpocetine Inhibits PDE1 to Increase Cerebral Blood Flow
A Mechanism-First Deep Dive on Vinpocetine's Vascular Effects in the Brain
8 min · 9 sources
Aviado Research
Aviado Research
May 42026
How Saffron's Crocin Targets Serotonin and BDNF Pathways for Mood
A Mechanism-First Deep Dive into Saffron's Neurobiological Effects and Clinical Impact
9 min · 8 sources
Aviado Research
Aviado Research
May 42026
How Rhodiola's Salidroside Activates AMPK to Boost Cellular Energy
From Cellular Pathways to Improved Aerobic Performance and Antioxidant Status
10 min · 12 sources
Aviado Research
Aviado Research
May 42026
Quercetin's Anti-Inflammatory Path: IL-6 Suppression vs Oxidative Defense
Contrasting Human Evidence for Cytokine Modulation and Antioxidant Enzyme Activation
10 min · 13 sources
Aviado Research
Aviado Research
May 42026
How PQQ Activates PGC-1α to Support Mitochondrial Function and Cognition
The Molecular Pathway Linking Pyrroloquinoline Quinone to Brain Health and Cellular Energy
8 min · 9 sources
Aviado Research
Aviado Research
May 42026
How Phosphatidylserine Enhances Acetylcholine Signaling in Brain Membranes
Membrane Integration, Cholinergic Pathways, and Cognitive Outcomes
9 min · 11 sources
Aviado Research
Aviado Research
May 42026
How Nicotinamide Riboside Boosts NAD+ to Power Cellular Energy Systems
Mechanisms and Human Evidence Linking NR, NAD+, and Mitochondrial Health
9 min · 15 sources
Aviado Research
Aviado Research
May 42026
9 min · 16 sources
Aviado Research
Aviado Research
May 42026
Black Cohosh's Triterpenes Target Serotonin Receptors, Not Estrogen
Clarifying the Mechanistic Pathways Behind Black Cohosh’s Relief of Menopausal Symptoms
9 min · 9 sources
Aviado Research
Aviado Research
May 42026
CoQ10's Dual Role: Electron Transport Plus Ferroptosis Protection
The mitochondrial and ferroptosis-blocking actions that underpin CoQ10’s clinical relevance
9 min · 9 sources
Aviado Research
Aviado Research
May 42026
L-Theanine's GABA-Glutamate Balance Drives Alpha Waves and Stress Response
Neurotransmitter Modulation and Brainwave Effects Underpin L-Theanine’s Relaxation and Focus Benefits
10 min · 12 sources
Aviado Research
Aviado Research
May 42026
GABA's Sleep Architecture Effect: Slow-Wave Enhancement Via GABAA Receptors
How GABA Supplementation Alters Sleep Stages and Efficiency Through Receptor Mechanisms
10 min · 12 sources
Aviado Research
Aviado Research
May 42026
How Bacopa's Bacosides Target Cholinergic & GABA Pathways for Memory
Mechanistic insights into Bacopa monnieri's dual cognitive and calming effects
8 min · 13 sources
Aviado Research
Aviado Research
May 42026
How Iron Controls Cellular Energy Through Mitochondrial Electron Transport
The essential role of iron-sulfur clusters and cytochrome complexes in powering ATP synthesis and human performance
9 min · 18 sources
Aviado Research
Aviado Research
May 42026
Citicoline Boosts Dopamine Receptors and Membrane Phospholipid Synthesis
Dual Mechanism Supports Cognitive and Motor Function in Human Trials
9 min · 10 sources
Aviado Research
Aviado Research
May 42026
8 min · 13 sources
Aviado Research
Aviado Research
May 42026
Cardiovascular Health Male 40 65·Knowledge Base·Preliminary
Cardiovascular Mastery for Men 40–65: Precision Strategies to Outpace Heart Disease
Why Your Next Decade Determines Your Lifelong Vascular Health
10 min · 3 sources
Aviado Research
Aviado Research
May 42026
Brain Health Midlife·Knowledge Base·Preliminary
Midlife Brain Health: The Professional Man’s Guide to Staying Sharp from 40 to 65
Why Cognitive Decline Begins Early—And What You Can Do About It, Backed by Science
11 min · 1 sources
Aviado Research
Aviado Research
May 42026
Immune System Health Inflammation·Knowledge Base·Preliminary
Immune Health After 40: Mastering the Balance Between Defense and Inflammation
A Comprehensive Guide for Men 40–65 to Reclaim Immune Resilience
11 min · 14 sources
Aviado Research
Aviado Research
May 42026
Cellular Longevity·Knowledge Base·Preliminary
Cellular Longevity: How Men 40-65 Can Slow Their Biological Clock
A Comprehensive Guide to the Science and Actions That Extend Your Healthspan
11 min · 1 sources
Aviado Research
Aviado Research
May 42026
Metabolic Health·Knowledge Base·Preliminary
Metabolic Health in Women 18-39: Beyond Calories, Into Hormones
A Comprehensive Guide to Tracking, Optimizing, and Understanding Your Metabolism in Your Reproductive Years
11 min · 9 sources
Aviado Research
Aviado Research
May 42026
Supplement Scanning·Knowledge Base·Preliminary
What Happens When You Scan a Supplement: From Bottle to Personalized Insights
A step-by-step look at how Aviado connects your supplements to better health decisions
5 min · 0 sources
Aviado Research
Aviado Research
May 42026
Cardiovascular Health Menopause·Knowledge Base·Preliminary
Cardiovascular Health After 40: Why Midlife Women Need a New Playbook
A Comprehensive Guide to Navigating Heart Health in Perimenopause and Beyond
12 min · 1 sources
Aviado Research
Aviado Research
May 42026
Perimenopausal Brain Health·Knowledge Base·Preliminary
Menopause and Your Brain: Mastering Cognitive Health After 40
A Comprehensive Guide for Women Navigating Hormonal Transitions
12 min · 1 sources
Aviado Research
Aviado Research
May 42026
Brain Function Cognitive Performance·Knowledge Base·Preliminary
Peak Mental Performance: The Comprehensive Guide for Men 18–39
How to Protect and Upgrade Your Brain for Life’s Most Demanding Decade
9 min · 10 sources
Aviado Research
Aviado Research
May 42026
Brain Mood Cognitive Performance·Knowledge Base·Preliminary
Your Brain Is Not Broken—It's Underfueled: The Nutritional Science of Women's Mood and Cognitive Performance
A Comprehensive Guide for Women 18-39 to Restore Focus, Mood, and Mental Clarity
10 min · 13 sources
Aviado Research
Aviado Research
May 42026
Sleep And Recovery·Knowledge Base·Preliminary
Sleep Is Your Superpower: The Essential Guide to Recovery for Men Under 40
How Deep, Consistent Sleep Fuels Testosterone, Metabolism, and Peak Performance
9 min · 6 sources
Aviado Research
Aviado Research
May 42026
Perimenopausal Sleep Disruption·Knowledge Base·Preliminary
Sleep After 40: Mastering Rest When Your Thermostat Fights Back
A Comprehensive Guide for Women Navigating Perimenopause and Menopause
11 min · 1 sources
Aviado Research
Aviado Research
May 42026
Cognitive Reserve·Knowledge Base·Preliminary
The Cognitive Reserve Buffer: Why Two Brains with the Same Damage Age So Differently
How Lifestyle, Biomarkers, and Interventions Build a Brain That Resists Decline
8 min · 1 sources
Aviado Research
Aviado Research
May 42026
Testosterone Hormonal Health·Knowledge Base·Preliminary
The Testosterone Crisis: How Men 18-39 Can Reclaim Hormonal Health—Without Injections
A Comprehensive Action Plan to Reverse Declining Testosterone and Thrive in Modern Life
11 min · 7 sources
Aviado Research
Aviado Research
May 42026
Hormonal Health·Knowledge Base·Preliminary
Hormonal Health in Your 20s and 30s: Why Your Menstrual Cycle Is Your Fifth Vital Sign
A Comprehensive Guide for Women Navigating Hormones, Fertility, and Health Data
9 min · 10 sources
Aviado Research
Aviado Research
May 42026
Hormonal Health Perimenopause·Knowledge Base·Preliminary
Hormonal Health After 40: Turning the Most Overlooked Transition Into Your Greatest Health Opportunity
A Comprehensive Guide to Navigating Perimenopause and Menopause with Precision and Data
11 min · 2 sources
Aviado Research
Aviado Research
May 42026
Gut Microbiome·Knowledge Base·Preliminary
Your Second Brain: The Gut Revolution Every Young Man Needs
Why fixing your gut changes everything—from mood to hormones to performance
11 min · 9 sources
Aviado Research
Aviado Research
May 42026
Brain Cognitive Biomarkers·Knowledge Base·Preliminary
The Four Blood Signals That Predict Brain Aging—and What Most Doctors Miss
A comprehensive action plan for your next doctor visit
10 min · 2 sources
Aviado Research
Aviado Research
May 42026
Why Collagen Supplements Exist in an Evidence Vacuum (And What That Means for Your Money)
A Comprehensive Guide to Collagen Science, Supplements, and What the Research Really Says
16 min · 15 sources
Aviado Research
Aviado Research
May 42026
8 min · 11 sources
Aviado Research
Aviado Research
May 42026
8 min · 10 sources
Aviado Research
Aviado Research
May 32026
Calcium's Hidden Metabolic Job: Why Your HDL, Triglycerides, and Blood Pressure All Respond Differently to the Same Dose
Personalizing Calcium for Metabolic Health Goes Beyond Bones
10 min · 8 sources
Aviado Research
Aviado Research
May 32026
Your Iron Status Is Quietly Distorting Your HbA1c — And Most Doctors Aren't Checking
Why personalizing your iron panel is the missing key to accurate metabolic health — and how to use supplement science to get it right
8 min · 10 sources
Aviado Research
Aviado Research
May 22026
Ashwagandha Is Not Just an Adaptogen: What Its Molecules Actually Do
Withanolides and related compounds appear to work through stress, GABA, inflammatory, and endocrine pathways - not one magic stress switch.
13 min · 14 sources
Aviado Research
Aviado Research
May 22026
8 min · 12 sources
Aviado Research
Aviado Research
Apr 222026
Saffron Matches SSRIs for Depression in Clinical Trials — So Why Does It Work for Some People and Not Others?
Exploring why saffron’s antidepressant benefits are so powerful for some — and invisible for others.
4 min · 5 sources
Aviado Research
Aviado Research
Apr 212026
NAC's Inflammation Effect Varies 10-Fold Across Studies — Your Baseline Oxidative Stress Determines Whether It Works
Why N-acetyl-cysteine is powerful for some, pointless for others — and how to know which group you’re in
4 min · 5 sources
Aviado Research
Aviado Research
Apr 192026
Berberine Works — But Only If Your Gut Can Activate It: The Microbiome Key Most Users Are Missing
Why gut health is the missing factor behind berberine's wildly inconsistent results
4 min · 5 sources
Aviado Research
Aviado Research
Apr 192026
4 min · 9 sources
Aviado Research
Aviado Research
Apr 182026
5 min · 8 sources
Aviado Research
Aviado Research
Apr 172026
L-Theanine Works Differently Alone vs. With Caffeine — And Most People Are Taking It Wrong
Understanding When L-Theanine Boosts Focus, When It Calms — and Why the Right Pairing Changes Everything
4 min · 4 sources
Aviado Research
Aviado Research
Apr 172026
4 min · 9 sources
Aviado Research
Aviado Research
Apr 122026
Creatine's Brain Benefits May Depend on Whether Your Brain Is Actually Creatine-Deficient
Research reveals why cognitive enhancement works for some but not others
5 min · 6 sources
Aviado Research
Aviado Research
Apr 102026
Zinc's Benefits Are Real — But Only If You're Actually Deficient
Meta-analyses reveal zinc supplementation dramatically improves metabolic markers in diabetics while potentially lowering HDL in healthy people
4 min · 8 sources
Aviado Research
Aviado Research
Apr 92026
CoQ10 Absorption Is Highly Variable — Your Form, Fat Intake, and Genetics May Determine Whether You're Getting Any Benefit
Why most people are taking a form their body can barely absorb
6 min · 6 sources
Aviado Research
Aviado Research
Apr 82026
Peak Mental Performance: The Comprehensive Guide for Men 18–39
How to Protect and Upgrade Your Brain for Life’s Most Demanding Decade
8 min · 10 sources
Aviado Research
Aviado Research
Apr 82026
Menopause and Your Brain: Mastering Cognitive Health After 40
A Comprehensive Guide for Women Navigating Hormonal Transitions
10 min · 1 sources
Aviado Research
Aviado Research
Apr 82026
Midlife Brain Health: The Professional Man’s Guide to Staying Sharp from 40 to 65
Why Cognitive Decline Begins Early—And What You Can Do About It, Backed by Science
9 min · 1 sources
Aviado Research
Aviado Research
Apr 82026
Your Omega-3 Index: The One Number That Explains Why Fish Oil Works for Some People and Does Nothing for Others
Why supplementing blind with fish oil misses the real difference-maker: your Omega-3 Index
4 min · 6 sources
Aviado Research
Aviado Research
Apr 72026
Why Your Curcumin Isn't Working: The Formulation Gap That Explains Conflicting Research
Meta-analyses reveal the hidden variable behind inconsistent curcumin studies
3 min · 5 sources
Aviado Research
Aviado Research
Apr 62026
Bacopa's 12-Week Delay Problem: Why Most People Quit Before the Cognitive Benefits Begin
New meta-analysis reveals why timing—not the supplement—determines who sees results
4 min · 7 sources
Aviado Research
Aviado Research
Apr 62026
Lion's Mane Works Chronically, Not Acutely — But Most People Are Dosing It Wrong
Why timing and duration, not dose size, determine whether you'll see cognitive benefits
4 min · 4 sources
Aviado Research
Aviado Research
Apr 62026
Brain Health After 55: Why Two-Thirds of Alzheimer's Patients Are Women
Estrogen depletion creates unique cognitive risks for post-menopausal women—but early neuroprotective action can change the trajectory
23 min · 11 sources
Aviado Research
Aviado Research
Apr 62026
Brain Health After 65: Defending Cognition When It Matters Most
Mild cognitive impairment affects 15-20% of adults over 65, but targeted interventions can meaningfully slow or prevent decline
24 min · 8 sources
Aviado Research
Aviado Research
Apr 62026
Brain, Mood & Cognitive Performance: Your Brain Is Not Broken, It Is Underfueled
The biological substrates of mood and cognition that every woman should track
23 min · 8 sources
Aviado Research
Aviado Research
Apr 42026
Gut Microbiome Biomarkers Guide·Explainer·Preliminary
The Leaky Gut Cascade: How Three Bloodwork Numbers Reveal Whether Your Microbiome Is Protecting or Attacking Your Intestinal Barrier
Understanding the measurable progression from dysbiosis to barrier breakdown to systemic inflammation
6 min · 7 sources
Aviado Research
Aviado Research
Apr 42026
Biological Aging Markers Guide·Explainer·Preliminary
The Clock vs. The Speedometer: Why Biological Age Measurement Has Two Fundamentally Different Jobs
Understanding the difference between where you are in aging and how fast you're aging
6 min · 12 sources
Aviado Research
Aviado Research
Apr 42026
Brain Cognitive Biomarkers Guide·Explainer·Preliminary
The Four Blood Signals That Predict Brain Aging — And Why Most Doctors Don't Test Them
How neurotrophins, plasmalogen lipids, inflammatory cytokines, and metabolic markers reveal brain health years before symptoms appear
5 min · 7 sources
Aviado Research
Aviado Research
Apr 32026
Stress Resilience Biomarkers·Explainer·Preliminary
The Cortisol Switch: How the MR/GR Receptor Balance Determines Whether Stress Makes You Stronger or Breaks You Down
Why identical stressors destroy some people and strengthen others
6 min · 15 sources
Aviado Research
Aviado Research
Apr 32026
Sleep Biomarkers·Explainer·Preliminary
The Autonomic Switch: Why Your HRV During Sleep Reveals What Your Sleep Tracker Can't
How Heart Rate Variability Exposes the Hidden Battle Between Your Sympathetic and Parasympathetic Nervous Systems
5 min · 9 sources
Aviado Research
Aviado Research
Apr 32026
Cardiovascular Biomarkers·Explainer·Preliminary
The Biomarker Cascade: How Your Heart Sends Distress Signals in a Specific Order — And Why Most People Only Get Tested When It's Almost Too Late
Understanding the sequential progression from endothelial dysfunction to structural damage reveals which biomarkers to track at each stage
5 min · 7 sources
Aviado Research
Aviado Research
Apr 32026
Cognitive Biomarkers·Explainer·Preliminary
The Cognitive Reserve Buffer: Why Two People With Identical Brain Scans Can Have Completely Different Mental Performance
How the brain's hidden resilience mechanism determines whether pathology translates into cognitive decline
6 min · 10 sources
Aviado Research
Aviado Research
Mar 312026
4 min · 11 sources
Aviado Research
Aviado Research
Mar 302026
4 min · 6 sources
Aviado Research
Aviado Research
Mar 292026
EPA vs DHA: The Ratio in Your Fish Oil Capsule Changes Everything — And Most People Are Taking the Wrong One
The overlooked EPA:DHA ratio in omega-3 supplements is the hidden lever behind inflammation, mood, and cholesterol outcomes
4 min · 6 sources
Aviado Research
Aviado Research
Mar 282026
Your Lactobacillus Strain Is the Variable: Why Most Probiotic Research Misses the Point
Network meta-analyses reveal only certain Lactobacillus strain combinations actually move the needle—are you taking the one that works for your biomarker?
4 min · 9 sources
Aviado Research
Aviado Research
Mar 252026
Phosphatidylserine Raised Acetylcholine in 12 Months — But Memory Improved While Cortisol Results Were All Over the Map
New research reveals why PS supplements work for some people but not others
4 min · 6 sources
Aviado Research
Aviado Research
Mar 242026
Alpha-GPC's Hidden Trade-Off: The Stroke Risk Signal That Changes How You Should Take It
A 10-year cardiovascular risk finding creates tension with proven cognitive benefits — demanding personalized monitoring over blind supplementation
4 min · 4 sources
Aviado Research
Aviado Research
Mar 242026
Citicoline Works for Stroke and Glaucoma — But Your Brain May Be a Different Story
Why citicoline's dramatic neuroprotection in brain injury doesn't translate to healthy brains—and how to know if you're a responder
4 min · 5 sources
Aviado Research
Aviado Research
Mar 222026
NAC's Mechanism Is Not What You Think: Why 'Antioxidant' Is the Wrong Label
How Cysteine, Glutathione, and Your Biology Decide If NAC Does Anything for You
22 min · 8 sources
Aviado Research
Aviado Research
Mar 192026
GABA Supplements Can't Cross the Blood-Brain Barrier — So Why Do Some People Swear By Them?
The surprising peripheral mechanisms that explain why oral GABA works for some but not others
18 min · 3 sources
Aviado Research
Aviado Research
Mar 172026
The omega-3 index as a status marker: what the proven blood response tells you that dose labels cannot
Why identical fish oil doses produce dramatically different blood levels—and why measuring your omega-3 index matters more than capsule milligrams
21 min · 6 sources
Aviado Research
Aviado Research
Mar 152026
Mtor 101·Explainer·Preliminary
mTOR: The Cell's Master Switch Between Growth and Survival
How cells decide whether to build new proteins or recycle old parts
14 min · 3 sources
Aviado Research
Aviado Research
Mar 152026
Insulin Signaling 101·Explainer·Preliminary
How Insulin Signaling Works: The Two-Fork Pathway That Controls Both Metabolism and Cell Growth
One receptor, two major cascades, and a critical branch point that shapes health and disease
16 min · 6 sources
Aviado Research
Aviado Research
Feb 102026
18 min · 5 sources
Aviado Research
Aviado Research
Feb 102026
22 min · 7 sources
Aviado Research
Aviado Research
Feb 102026
22 min · 7 sources
Aviado Research
Aviado Research
Feb 102026
22 min · 15 sources
Aviado Research
Aviado Research
Feb 102026
22 min · 15 sources
Aviado Research
Aviado Research
Feb 102026
21 min · 8 sources
Aviado Research
Aviado Research
Feb 82026
Homocysteine·Knowledge Base·Strong
Best Supplements for Homocysteine: What the Evidence Actually Shows
12 min · 15 sources
Aviado Research
Aviado Research
Feb 82026
Cortisol·Knowledge Base·Moderate
Best Supplements for Cortisol (Stress Hormone): What the Evidence Actually Shows
12 min · 8 sources
Aviado Research
Aviado Research
Supplements, A to Z
84 ingredients